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How does capsaicin work to relieve pain?

Harris H. McIlwain, MD
Rheumatology
Hot peppers contain a substance called capsaicin. When capsaicin is applied regularly to a part of the body, substance P (the neuropeptide that carries pain signals) becomes depleted in that location. Studies show that when substance P is reduced in an area on the body, pain is reduced, too. This also explains why people who consume many hot peppers gradually build up a tolerance.
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Diet for a Pain-Free Life: A Revolutionary Plan to Lose Weight, Stop Pain, Sleep Better and Feel Great in 21 Days, ADA...sound nutritional advice...do-able, delicious..a godsend to pain sufferers.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.