Can Xodol interact with other medications or foods?

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The prescription pain medication Xodol (hydrocodone and acetaminophen) may interact with other drugs, possibly raising your risk for harmful side effects. Before taking Xodol, give your doctor and pharmacist a list of all your other drugs (prescription and nonprescription) and dietary and herbal supplements. Once you begin taking Xodol, do not take any new drug or supplement without checking with your doctor or pharmacist first. Keep a copy of your list in your wallet or purse in case of emergency. Be especially careful to mention if you take any of the following drugs, which may interact with Xodol:
  • any other drug containing acetaminophen, including some nonprescription cough and cold medicines (read labels carefully)
  • antidepressants
  • antipsychotic medicines
  • antihistamines
  • drugs to treat anxiety
  • other narcotic medicines
  • sedatives, sleeping pills or tranquilizers
  • medications for irritable bowel syndrome
  • motion sickness medicines
  • the inhaler drug ipratropium
  • antiseizure medications
  • drugs that treat Parkinson's disease
  • anti-ulcer medications
  • medicines for urinary problems
  • blood-thinning medication such as warfarin
Do not drink alcohol while you're taking Xodol, because the combination can dangerously intensify the drug's effects.