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Can I use Tylox if I am taking nalmefene?

If you are taking nalmefene a drug used to reverse an opioid overdose, you should not take Tylox (acetaminophen and oxycodone). Tylox, which is prescribed to treat moderate to moderately severe pain, contains oxycodone, an opioid (narcotic) pain reliever. Combining Tylox with nalmefene can block the pain-relieving effects of oxycodone. In addition, because Tylox and nalmefene have opposing effects, taking them together can cause withdrawal symptoms.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.