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Can I use Tylox if I am taking isoniazid?

If you are taking isoniazid (Tubizid) for the treatment of tuberculosis, you should not take Tylox (acetaminophen and oxycodone). The two drugs together can cause you to accumulate large amounts of oxycodone, an opioid (narcotic) that's one of the two active ingredients in Tylox, in your body, raising the risk of breathing problems. Isoniazid can also interact with the other active ingredient in Tylox, acetaminophen, to put you at risk for liver problems. Tylox is prescribed to treat moderate to moderately severe pain on an as-needed basis.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.