Can I use Magnacet if I have a history of thyroid problems?

You can take the prescription pain medication Magnacet (oxycodone and acetaminophen) if you have hypothyroidism (a low-functioning thyroid). However, your thyroid condition may affect how much and how often you should take Magnacet. Before you start taking Magnacet, let your doctor know if you have a sluggish thyroid and how much hormone you're taking to treat it.