Can I use Demerol if I am taking a monoamine oxidase inhibitor (MAOI)?

You should not take the prescription pain medication Demerol (meperidine) if you're taking a monoamine oxidase inhibitor (MAOI) or have taken one within the last 14 days. In combination with Demerol an MAOI can cause complications ranging from fever and diarrhea to shock, coma and death.

MAOIs are typically used to treat depression; examples include:
  • phenelzine (Nardil)
  • tranylcypromine (Parnate)
  • isocarboxazid (Marplan)
  • selegiline (Eldepryl)

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.