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Can I use Demerol if I have a history of kidney disease?

If you have a history of kidney disease or kidney tumors, talk to your doctor before taking Demerol (meperidine), a prescription drug for moderate to severe short-term pain. Kidney problems can cause too much Demerol to build up in your system. You doctor will want to consider this when figuring out your dosage and how often you should take the drug.