Can I use Tylox if I have a history of urinary problems?

If you have a history of urinary problems, such as a narrowing of your urethra (the tube that urine passes through), low urinary output (oliguria) or an enlarged prostate, your doctor may be cautious about prescribing Tylox (acetaminophen and oxycodone) for you. The oxycodone in this drug, which is used to treat moderate to moderately severe pain on an as-needed basis, is an opioid (narcotic) that may cause you to retain urine. Coupled with your other urinary problems, this could lead to infection, bladder damage or kidney damage.