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Can Tylenol with Codeine interact with other medications or foods?

Tylenol with Codeine (acetaminophen and codeine) is not known to interact with food, but it may interact with other medications. Before taking this prescription pain reliever for treating mild to moderate pain, tell your doctor and pharmacist about all your other medications (prescription and over-the-counter) and supplements you take. It's especially important to let your doctor know if you take any of the following, which are more likely to interact with Tylenol with Codeine:
  • any product containing acetaminophen
  • an antidepressant
  • any medication for cough, cold or allergies
  • another pain reliever
  • a sedative, sleeping pill or tranquilizer
  • vitamins
Drinking alcohol while taking Tylenol with Codeine is dangerous. Because it increases the risks of serious side effects including extreme drowsiness, breathing problems and liver damage, you should avoid it.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.