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Can I use Percodan if I'm taking gout medication?

If you are taking gout medications, ask your doctor if you can take Percodan, a strong pain reliever that is a combination of oxycodone and aspirin. Doctors prescribe a number of different kinds of drugs for gout; some can cause problems in combination with Percodan, while others don't interact with the drug. Here are some of the drugs that can be prescribed for gout:
  • Colchicine: This gout drug does not typically interact with Percodan.
  • Corticosteroid drugs: These can increase the likelihood that aspirin will cause problems in the gastrointestinal tract. Corticosteroids also affect how quickly aspirin is cleared from the body, so your doctor may need to adjust your dose.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs): You should avoid combining NSAIDs with Percodan because both increase the risk of bleeding in the gastrointestinal tract. The combination can also raise the risk of kidney damage.
  • Opioid drugs: Doctors sometimes prescribe strong opioid medications for the pain of gout. Oxycodone is also an opioid, so combining these drugs raises the risk of an overdose.
  • Uric acid reducers: Aspirin can interfere with the workings of the uric acid reducers probenecid and sulfinpyrazone, so you should not take Percodan if you're on either of these drugs.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.