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Can I use Magnacet if I am taking isocarboxazid?

The prescription pain medication Magnacet (oxycodone and acetaminophen) is not recommended for people who take isocarboxazid (Marplan) or have used it in the past 14 days. The antidepressant isocarboxazid belongs to a group of drugs called monoamine oxidase inhibitors (MAOIs) that can increase the potency of narcotic pain medications like Magnacet. The result can be overdose symptoms, including serious breathing problems, low blood pressure, seizures, coma and death. Before starting Magnacet, let your doctor know if you use isocarboxazid or have used it in the past.

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