Can I use Lortab if I have a history of liver disease?

You may be able to take the prescription pain medication Lortab (hydrocodone and acetaminophen) if you have a history of liver disease, but you should tell your doctor about your medical condition before you start the drug. Your doctor may decide that it's not safe for you to take Lortab; if your doctor does prescribe it, he or she is likely to monitor you closely. Be sure not to take more of the drug, or take it more frequently, than your doctor prescribed. Getting too much acetaminophen is particularly dangerous for people with liver problems.