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What should I know about pentazocine and naloxone before taking it?

Before taking pentazocine and naloxone, you should know that an allergic reaction is possible, so do not take it if you are allergic to any of its ingredients. You also should know that pentazocine and naloxone can cause drowsiness and dizziness. Other situations and substances can increase these effects. For instance, drinking alcohol, taking certain medications (such as sedatives), exercising, being in hot weather and having a fever can increase the dizziness and drowsiness caused by pentazocine and naloxone. Try to avoid driving or working with heavy machinery while taking the drug. Before taking pentazocine and naloxone, you should also understand that this drug can cause dependence. Do not take this drug if you have ever had a dependence problem with narcotics or if you have diarrhea or are taking sodium oxybate. Other medical conditions may be complicated by using this drug. These include: having a history of blood or electrolyte problems, porphyria (a genetic problem affecting your skin or nervous system), an enlarged prostate, increased pressure in the brain, seizures, high blood pressure, heart problems, underactive thyroid, breathing or lung problems, adrenal gland problems, liver or kidney conditions, difficulty urinating, a bladder or urethra blockage, gallbladder problems, stomach or intestinal problems, a recent head injury or brain tumor, muscle problems, mental or mood problems, suicidal thoughts or heart attack.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.