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What should I know about aspirin/oxycodone before using it?

Before using aspirin and oxycodone know that:

  • Allergic reactions can occur if you are allergic to either ingredient or to certain other drugs, including codeine or some non-steroidal anti-inflammatory drugs (NSAIDs). 
  • You should not take this drug with other medications unless approved by a doctor, as serious interactions can occur.
  • The medication can become addictive, and should therefore be taken exactly as prescribed.
  • Using this drug with non-prescription (over-the-counter) medications also containing aspirin can result in too much aspirin in the body.
  • Oxycodone can cause sleepiness so care should be taken when driving or performing jobs that require alertness.
  • You should inform your doctor if you have blood disorders (including hemophilia), or are taking medications that affect the blood (e.g., anti-coagulants) to avoid possibly serious side effects.
  • This medication might not be recommended if you are not in good overall health or will be having surgery.
  • Missed doses should be taken as soon as you remember it, unless it is almost time for the next dose. Do not take multiple doses to make up for a missed dose.

The following conditions should be discussed with your doctor before taking aspirin and oxycodone: adrenal problems, aneurysm, blockage of your bladder, chicken pox or flu symptoms, curvature of the spine, dehydration, enlarged prostate, heart problems, history of alcohol or other substance abuse or dependence, history of mental or mood problems, history of recent head injury, hives, increased pressure in the brain, Kawasaki syndrome, kidney or liver problems, low blood pressure, low blood volume, lung or breathing problems, pancreas or gallbladder problems, rheumatic condition, seizures, severe drowsiness, shock caused by heart problems, sleep apnea, stroke, stomach or bowel problems, suicidal thoughts or attempts, symptoms of alcohol withdrawal, trouble urinating, tumors and underactive thyroid.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.