Secondary amenorrhea may result from excess uterine lining. This condition, called endometrial hyperplasia, can lead to uterine cancer. It can also be a sign of another serious condition, such as an eating disorder, drug addiction, a blood disorder, or a chronic disorder of organs like the liver, kidneys, lungs, or digestive tract.
Women who are concerned with fertility may be more seriously impacted by secondary amenorrhea. Absence of menstruation generally means that you are not ovulating. Without ovulation, conception can be very difficult and can make secondary amenorrhea a serious problem for women who are trying to conceive. This can be emotionally difficult for women.