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What role does genetics play in developing Alzheimer's disease?

The role of genetics in developing Alzheimer's disease continues to be extensively investigated, and studies support that late-onset Alzheimer's disease is attributed to the having the apolipoprotein E (ApoE) gene. People inherit one form of the ApoE gene (e2, e3 or e4) from each parent. Those who inherit the e4 form of the ApoE gene from one parent have an increased risk of developing Alzheimer's disease, and those who inherit the e4 gene from both parents have an even higher risk of developing Alzheimer's disease.

Other risk factors related to Alzheimer's disease include lifestyle factors such as diet, physical and mental exercise. These are pretty easy to modify and may make a difference in your risk of developing Alzheimer's disease.

 

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.