If you have HIV (human immunodeficiency virus), a high white blood cell count can reduce your risk of developing AIDS-related cancer. For example, Kaposi sarcoma - a common AIDS-related cancer - usually strikes people with white blood cell counts (also called CD4 counts) under 200 to 300. Non-Hodgkin lymphoma usually strikes when the count dips below 100, and primary central nervous system lymphoma occurs most often when the count falls below 50.
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