Addison's disease is an endocrine, or hormone, disorder that causes a shortage of all the adrenal hormones. One of these hormones is cortisol, which affects almost every part of the body. Cortisol helps the body respond to stress, maintains blood sugar levels, and regulates blood pressure. Aldosterone is another important hormone affected by Addison's disease. Aldosterone helps maintain blood pressure and helps the kidneys regulate the balance of salt and water in the blood.
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