What are the risks of taking acetaminophen?

Acetaminophen is a mainstay in the medicine cabinets of many American households. When used at recommended levels, the drug is safe and highly effective. But acetaminophen also can be dangerous when not used properly.

Acetaminophen poisoning is a significant cause of liver damage, which can lead to the need for a lifesaving liver transplant. While some cases of acetaminophen overdose are intentional, many stem from an individual unknowingly taking too much until the medication reaches dangerous levels in the body.

Acetaminophen poisoning does not always result in irreversible liver damage. "Most people improve without going into liver failure," notes Ronald Busuttil, MD, PhD, director of the Dumont-UCLA Transplant Center. "Not everyone who takes too much acetaminophen is going to end up needing a liver transplant. But although it is a small percentage of people, the number who do require transplantation is significant."

The biggest risk of taking too much acetaminophen is that is can cause liver damage, which has a variety of symptoms that can lead to liver failure. Watch pain management expert Devi Nampiaparampil, MD, explain these risks and suggest solutions.

Continue Learning about Acetaminophen

What happens if I miss a dose of acetaminophen?
Stacy Wiegman, PharmDStacy Wiegman, PharmD
Acetaminophen is usually taken as needed for pain relief, so missing a dose will mean that it will j...
More Answers
How effective is acetaminophen for treating migraine?
Dr. Darria Long Gillespie, MDDr. Darria Long Gillespie, MD
Acetaminophen reduces moderate to severe migraine pain down to mild pain within 2 hours for about 50...
More Answers
What is Acetaminophen?
What is Acetaminophen?
How to Bring Down a HIgh Fever
How to Bring Down a HIgh Fever

Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.