ACE Inhibitor

Why does Lisinopril cause cough as a side effect?

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  • A answered

    Lisinopril is in the class of angiotensin-converting enzyme (ACE) inhibitors, which has a dry, persistent cough as a side effect for all of the medications in this class. The exact reason behind why such cough occurs is not completely understood. Although blocking the angiotensin-converting enzyme (ACE) helps control blood pressure, it may also cause the build up of certain natural substances such as bradykinin and substance P which is thought to cause coughing.  If this side effect is still bothering you, you should follow up to see if your doctor is willing to consider other treatment options. 

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