Who should not take Zestril?

Anyone with a history of angioedema (swelling under the skin on the face, neck, hands or other areas) should not take Zestril (lisinopril), which treats high blood pressure, heart failure and certain other heart conditions. People who have had an allergic reaction to it in the past, or to angiotensin converting enzyme (ACE) inhibitors, which are other drugs used to treat hypertension and heart failure, should not take Zestril either.

If you're pregnant, you should avoid Zestril if possible. Call your doctor immediately if you become pregnant while taking it.