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What is captopril and hydrochlorothiazide?

Captopril-hydrochlorothiazide (HCTZ) is a combination drug used to treat people with high blood pressure. The diuretic, hydrochlorothiazide, keeps the body from retaining water, and the angiotensin-converting enzyme (ACE) inhibitor, captopril, stops the body from producing enzymes that normally cause arteries to constrict. The combination of these two drugs relaxes the arteries and reduces the amount of fluid that the heart needs to pump, which lowers blood pressure. Captopril-HCTZ is available under the brand name Capozide.

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