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What should I know about captopril-hydrochlorothiazide before taking it?

The drugs that can interact with captopril-hydrochlorothiazide (HCTZ) include:

  • other diuretics
  • salt substitutes
  • alcoholic drinks
  • barbiturates
  • diabetes medications
  • gout medications
  • ibuprofen and other nonsteroidal anti-inflammatory drugs (NSAIDS
  • potassium supplements
  • cholesterol-lowering medications
  • lithium
  • prescription pain medications
  • muscle relaxers
  • blood thinners
  • calcium supplements
  • digoxin
  • methenamine
  • angina medication
  • certain antidepressants
  • prednisone and other corticosteroids
  • amphotericin B

Tell your doctor about any medications or supplements you are taking before starting treatment with captopril-HCTZ. Women who are pregnant should not take captopril-HCTZ, as it has been known to cause birth defects. This drug may not be the best choice for you if you have asthma, congestive heart failure, diabetes, gout, kidney disease, liver disease, lupus or an allergy to sulfa drugs. Stay out of the sun and avoid tanning while using captopril-HCTZ, as it causes increased susceptibility to sunburn. Because this medication can cause dizziness or drowsiness, avoid driving or operating machinery until you know how your body reacts.

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Important: This content reflects information from various individuals and organizations and may offer alternative or opposing points of view. It should not be used for medical advice, diagnosis or treatment. As always, you should consult with your healthcare provider about your specific health needs.