Can I take Prinivil if I have a history of kidney disease?

If you have a history of kidney disease, you may be able to take Prinivil (lisinopril). If your kidney disease is moderate or severe, your doctor may lower your dose and monitor you for side effects.

Prinivil is an angiotensin converting enzyme (ACE) inhibitor and, as such, can increase levels of blood urea nitrogen (BUN) and serum creatinine, both markers of kidney function. High levels indicate kidney impairment. This is more common in people with renal artery stenosis (narrowing of the renal artery) and those taking diuretics. Treatment with ACE inhibitors such as Prinivil has been shown to slow the progression of kidney disease.

People with kidney disease may also experience a reduction in white blood cells. If you have a history of kidney disease, your doctor will likely do a complete blood count (CBC) before prescribing Prinivil and during treatment.

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