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Can I take Prinivil if I have a history of scleroderma?

If you have a history of scleroderma, your doctor will likely have you take a blood test before prescribing Prinivil (lisinopril). A complete blood count (CBC) is especially important if your scleroderma affects your kidneys.

Prinivil is an angiotensin converting enzyme (ACE) inhibitor and, as such, can affect kidney function and cause kidney impairment. While taking Prinivil, people with scleroderma may also experience neutropenia, a low white blood cell count, or agranulocytosis, in which the bone marrow does not make enough white blood cells. Your doctor will most likely monitor your white blood cell counts during treatment. Prinivil is prescribed to treat high blood pressure and congestive heart failure and to boost the odds of survival after heart attack.

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