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Dr. Matthew Karpenko, DO

Dr. Matthew Karpenko, DO

Age 47 Oncology M
(31) 31 reviews

Telehealth available

Accepting New Patients


Dr. Matthew Karpenko, DO is a oncology specialist in Orangeburg, SC. Dr. Karpenko completed a residency at 2005 Chief Resident. He currently practices at The Mabry Center for Cancer Care and is affiliated with Grand Strand Medical Center. He accepts multiple insurance plans. Dr. Karpenko is board certified in Hematology.


  • 2005 Chief Resident, Residency Hospital
  • Ohio State University, Fellowship Hospital — 2008
  • United Health Services Hospitals, Residency Hospital — 2005
  • United Health Services, Internship Hospital — 2002
  • Syracuse University, Undergraduate School — 1996

Insurance Accepted

  • Accepts most major Health Plans. Please contact our office for details.
  • Aetna
  • CareFirst Blue Cross Blue Shield
  • Cigna
  • MultiPlan

* Please verify this information when scheduling an appointment.


  1. Practice

    1. 1
      The Mabry Center for Cancer Care
      1161 Cook Rd, Orangeburg, SC 29118 Existing Patients: (803) 395-4600
    2. 2
      Peninsula Regional Medical Center
      100 E Carroll St, Salisbury, MD 21801 Existing Patients: (410) 543-7100

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Met him in NC. Explains things well that I can understand. Communicates well, kind, and compassionate. Available to answer questions- has even called me to check in. Highly recommended.
T.K. — Jul 18, 2021
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Dr. Matthew Karpenko, DO
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Frequently Asked Questions

Dr. Karpenko frequently treats Pancreatic Neoplasms, Renal Neoplasms & Resection, and Blood Disorders.  

Find contact information here to make an appointment.

Hospital Affiliations

  • Grand Strand Medical Center
  • Guthrie Cortland Regional Medical Center