His specialized interests include novel approaches to cancer management, cancer prevention, and advanced radical laparoscopic (minimally invasive) surgery including robotic surgery. Dr. Nagarsheth has performed extensive research on the mechanisms of cancer prevention, including the hormonal manipulation of apoptosis. He is a lead author on a landmark study that provides the most convincing evidence yet for a novel theory of how birth control pills help prevent ovarian cancer. He has continued his research at Mount Sinai evaluating the role of hormonal effects on gynecologic organs, and has developed an extensive research background in blood management in the field of Gynecologic Oncology. Currently, Dr. Nagarsheth is considered one of the world's experts in performing Bloodless Surgery in Gynecologic Oncology. He speaks frequently at national meetings and serves as a principal investigator for several national clinical trials. Recently, Dr. Nagarsheth was invited by Fran Drescher (U.S. Public Diplomacy Envoy for Women's Health Issues, Founder and Visionary, Cancer Schmancer Movement, and television star) to serve on the medical advisory board for the Cancer Schmancer Movement.
In 2008, Dr. Nagarsheth joined together with five other Gynecologic Oncologists from around the country, with the support of the Gynecologic Cancer Foundation, and began an international campaign to raise awareness for gynecologic cancers through music and the arts. Dr. Nagarsheth and his talented colleagues formed the rock band N.E.D. (which stands for No Evidence of Disease) and landed a record deal with Motema Music, NYC. Their self-entitled album was released in September 2009 to rave reviews.
Dr. Nagarsheth also has been honored with a book deal from Jones and Bartlett Publishing and has written Music and Cancer, A Prescription for Healing. This book is receiving top reviews from prominent individuals ranging from celebrity cancer survivors to the Past President of the American Cancer Society and the Presidential Appointed Chair of the National Cancer Advisory Board. The book has been described as a 'must have' handbook for cancer patients and their caregivers. Proceeds from both the N.E.D. album and book are being used to start the N.E.D. Cancer Foundation, an organization founded by Dr. Nagarsheth and his colleagues with a vision on improving the quality of life of patients with gynecologic cancers.