Clinical Interests: Medical Genetics, Pediatric Genetics, Inborn Errors of Metabolism, Lysosomal Storage Diseases, Newborn Screening, Urea Cycle Disorders, Hyperammonemia, Fatty Acid Oxidation Defects, Organic Acidemias, Maple Syrup Urine Disease
Dr. Wasserstein is the Director of the Program for Inherited Metabolic Diseases (PIMD) at Mount Sinai Medical Center. This program is one of the largest metabolic disease treatment programs in the country, treating several hundred patients who are diagnosed with rare inborn errors of metabolism. The PIMD is a New York State Newborn Screening designated referral center for infants with inherited metabolic diseases, and is also the leading referral center in the region for the evaluation of patients with suspected inborn errors of metabolism. Disorders that are treated at the PIMD include:
Dr. Wasserstein is part of Mount Sinai's International Center for Types A and B Niemann-Pick disease. She is also a clinical researcher, focusing on evaluating the safety and effectiveness of novel treatments for patients with inborn errors of metabolism.
In the News: Dr. Wasserstein discusses testing babies for metabolic disorders in the The Daily News feature, The Daily Check Up.
Wasserstein MP, Buchsbaum MS, Sansaricq C, Snyderman SE. Cerebral glucose metabolism in patients with early treated classical phenylketonuria. Molec Genet Metab 2006 March; 87: 272-277.
Wasserstein MP, Desnick RJ, Schuchman EH, McGovern MM, Wallenstein S, Lamm C, Hossain S. Natural history of type B Niemann-Pick Disease: results from a ten. Pediatrics 2004 Dec; 114(6): 672-677.
Salomons GS, Gibson KM, Landegge Pope L, Errami A, Potter M, Nowaczyk M, Olpin S, Manning N, Raiman JJ, Slade T, Champion MP, Peck D, Gavrilov D, Hillman R, Hoganson GE, Donaldson K, Shield JH, Ketteridge D, Wasserstein MP, Jakobs C. Clinical, enzymatic and molecular characterization of nine new patients with malonyl-coenzyme A decarboxylase deficiency. J Inherit Metab Dis 2007 Feb; 30(1): 23-28.
McGovern MM, Aron A, Wasserstein MP, Desnick RJ, Brodie SE. Natural history of Type A Niemann-Pick disease: possible endpoints for therapeutic trials. Neurology 2006 Jan 24; 66(2): 228-232.
Willis A, Vanhuse C, Newton K, Wasserstein M, Morotti R. Farber Disease Type IV Presenting with Cholestatic Jaundice and neonatal liver failure:Report of Two Cases. Pediatr Dev Pathol 2007 Sept; 28(1).
Melissa P. Wasserstein, MD's contact info
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