Brad Spellberg

Bio

Dr. Brad Spellberg, a Sharecare expert, is an Associate Professor of Medicine at the David Geffen School of Medicine at UCLA and the Harbor-UCLA Medical Center.  He received his BA in Molecular Cell Biology-Immunology in 1994 from UC Berkeley.  He then attended medical school at the Geffen School of Medicine at UCLA, where he received numerous academic honors, including serving as the UCLA AOA Chapter Co-President, and winning the prestigious Stafford Warren award for the topic academic performance in his graduating class.  Dr. Spellberg completed his Residency in Internal Medicine and subspecialty fellowship in Infectious Diseases at Harbor-UCLA Medical Center, where he received the Department of Medicine Subspecialty Fellow of the Year award.


Dr. Spellberg works as an academic hospitalist, attending on the inpatient medicine wards.  His research is diverse, ranging from basic immunology and vaccinology to pure clinical research and outcomes research.  His laboratory research has focused on developing a vaccine that targets the bacterium Staphylococcus aureus and the fungus Candida; the vaccine is undergoing clinical development.  Dr. Spellberg is currently working on the immunology and vaccinology of highly resistant Acinetobacter infections.  He also has served as the PI of a multi-centered, randomized, double-blinded placebo controlled study of iron chelation adjunctive therapy for mucormycosis.  More recently, Dr. Spellberg has begun research programs in infection prevention, using a novel disinfectant technology, and healthcare policy research focusing on medical education and medical documentation.  Dr. Spellberg serves as Medical Director for Clinical Research Solutions, a clinical trials unit co-founded with Dr. Darrell Harrington, Chief of General Internal Medicine, which supports conduct of clinical research at Harbor-UCLA Medical Center.


Dr. Spellberg has worked with the Infectious Diseases Society of America (IDSA) to attempt to bring attention to the problems of increasing drug resistance and decreasing new antibiotics.  His research regarding new drug development has been a cornerstone of the IDSA’s white paper, Bad Bugs, No Drugs, and has been cited extensively in medical literature and on Capitol Hill.  He is a Fellow in the IDSA and joined the IDSA’s Antimicrobial Availability Task Force (AATF) to continue working on this critical problem.  As a member of the AATF, he has first-authored a consensus IDSA position paper on the appropriate clinical trial design for Community Acquired Pneumonia, a multi-society position paper on clinical trial conduct for nosocomial pneumonia, and a systematic review of historical literature as a basis for conducting clinical trials for skin infections.  Finally, Dr. Spellberg is the author of Rising Plague, which he wrote to inform and educate the public about the crisis in antibiotic resistant infections and lack of antibiotic development.



Specialties:

  • infectious disease

Affiliation:

  • David Geffen School of Medicine at UCLA and the Harbor-UCLA Medical Center

Location:

Activity

  • Sharecare News
    Sharecare News posted a story about Infectious Disease:

    MONDAY, June 17 (HealthDay News) -- The younger you are, the less likely you are to realize you are infected with HIV or receive treatment for it, a new study finds.

    Early diagnosis, prompt and continued care, and antiretroviral drug therapy are key to lowering the risk of illness and dea...Full Article

  • Sharecare News
    Sharecare News posted a story about Infectious Disease:

    FRIDAY, June 14 (HealthDay News) -- Certain proteins in saliva help protect seniors from influenza, according to a new study from China.

    The findings improve understanding of why older people are better able to fight off the new strains of bird and swine flu than younger people, said rese...Full Article

  • Sharecare News
    Sharecare News posted a story about Infectious Disease:

    THURSDAY, June 13 (HealthDay News) -- This past flu season started earlier, peaked earlier and led to more adult hospitalizations and child deaths than most flu seasons, U.S. health officials reported Thursday.

    At least 149 children died, compared to the usual range of 34 to 123, accordi...Full Article

  • Sharecare News
    Sharecare News posted a story about Infectious Disease:

    THURSDAY, June 13 (HealthDay News) -- A close look at some very old bones is shedding light on the elimination of leprosy in Europe, where it was a major scourge until medieval times.

    Leprosy was common across medieval Europe and nearly one in 30 people are thought to have had the disease...Full Article

  • Sharecare News
    Sharecare News posted a story about Infectious Disease:

    WEDNESDAY, June 12 (HealthDay News) -- An antiviral drug may help protect injection drug users from HIV infection, a new study finds.

    The study of more than 2,400 injection drug users recruited at 17 drug treatment clinics in Thailand found that daily tablets of tenofovir reduced the risk...Full Article

  • Sharecare News
    Sharecare News posted a story about Infectious Disease:

    THURSDAY, June 6 (HealthDay News) -- Anyone who has watched the movie "Contagion" has seen how fast a virus can spread and how deadly it can be, but is it reality?

    Much like the film, a new emerging virus called the Middle East respiratory syndrome coronavirus (MERS-CoV), which kills ha...Full Article

  • Sharecare News
    Sharecare News posted a story about Infectious Disease:

    THURSDAY, June 6 (HealthDay News) -- Genetic mutations in two emerging "bird" flu viruses could turn them into potential sources of pandemics, Massachusetts Institute of Technology researchers report.

    One expert who was not involved with the new studies, however, said virus changes that m...Full Article

  • Sharecare News
    Sharecare News posted a story about Infectious Disease:

    WEDNESDAY, June 5 (HealthDay News) -- Women are less likely to develop infections related to receiving health care than men, according to a large new study.

    After examining thousands of cases involving hospitalized patients, researchers found that women were at much lower risk for bloodst...Full Article

  • Sharecare News
    Sharecare News posted a story about Infectious Disease:

    THURSDAY, May 30 (HealthDay News) -- People with a severe case of the flu don't benefit from taking double doses of the antiviral drug Tamiflu, according to a new study conducted in Southeast Asia.

    Tamiflu (oseltamivir) stocks could be conserved during pandemics if doctors prescribe only ...Full Article

  • Sharecare News
    Sharecare News posted a story about Infectious Disease:

    WEDNESDAY, May 29 (HealthDay News) -- Since the start of last year's outbreak of fungal meningitis cases linked to tainted steroid injections, federal health officials have recommended three to six months of antifungal therapy to combat potentially fatal infections.

    But health officials r...Full Article

  • Sharecare News
    Sharecare News posted a story about Infectious Disease:

    WEDNESDAY, May 29 (HealthDay News) -- Gene therapy that turns cells in the nose into factories that crank out super antibodies against the flu protected mice and ferrets against lethal doses of several pandemic strains of the virus.

    If the approach works in humans, it could offer several ...Full Article

  • Sharecare News
    Sharecare News posted a story about Infectious Disease:

    TUESDAY, May 28 (HealthDay News) -- Chinese scientists say they've identified the first cases of resistance to the flu drug Tamiflu in a person infected with the emerging H7N9 avian flu virus.

    According to BBC News, there have been 131 confirmed cases in China of the new "bird" flu...Full Article

  • Sharecare News
    Sharecare News posted a story about Infectious Disease:

    MONDAY, May 20 (HealthDay News) -- The older vaccine for whooping cough that was phased out in the late 1990s is more effective than the current version of the vaccine, a new study contends.

    Teenagers who received four shots with the older vaccine -- called whole-cell vaccine -- before th...Full Article

  • Sharecare News
    Sharecare News posted a story about Infectious Disease:

    FRIDAY, May 17 (HealthDay News) -- Liver transplants to treat a common type of liver cancer are a viable option for people infected with HIV, according to new research.

    The Italian study, published May 10 in the journal The Oncologist, found that the AIDS...Full Article

  • Sharecare News
    Sharecare News posted a story about Infectious Disease:

    MONDAY, May 13 (HealthDay News) -- Higher-than-normal temperatures last year may have led to an increase in West Nile virus cases, say U.S. health officials.

    More deaths from West Nile virus were reported in 2012 -- 286 in all -- than in any year since 1999, when the mosquito-borne diseas...Full Article