What percentage of breast cancer cases are due to the BRCA1 or BRCA2 genes?
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NorthShore University HealthSystem answered:Women with BRCA mutations face about a 50-85% lifetime risk. Women at average risk of breast cancer face about a 12% lifetime risk. In addition, BRCA1/2 breast cancers can emerge very young in life, i.e., the 20s, well before breast cancer screening is routinely advised. It is also important to note that BRCA1/2 carriers face about a 40% risk of ovarian cancer.Women with BRCA mutations face about a 50-85% lifetime risk. Women at average risk of breast cancer face about a 12% lifetime risk. In addition, BRCA1/2 breast cancers can emerge very young in life, i.e., the 20s, well before breast cancer... More -
Shelly Weiss of NorthShore University HealthSystem answered:There are different genes that play a role in genetic breast cancer, but BRCA1 and BRCA2 are the most common. In the category of genetic breast cancer (accounting for ~5-10% of all breast cancers) 80%-90% percent is due to alterations in BRCA1 and BRCA2.
There are different genes that play a role in genetic breast cancer, but BRCA1 and BRCA2 are the most common. In the category of genetic breast cancer (accounting for ~5-10% of all breast cancers) 80%-90% percent is due to alterations in... More

