What is primary progressive multiple sclerosis (PPMS)?

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  1. Multiple sclerosis (MS) is a disease that affects the nervous system. In a healthy body, nerves are surrounded by a protective layer of fatty tissue called the myelin sheath. If you have MS, that fatty layer is irreversibly damaged by an unknown cause. This makes it harder for your nerves to transmit impulses between your brain, eyes, and spinal cord, causing a range of symptoms.

    Primary-progressive multiple sclerosis (PPMS) is a form of multiple sclerosis (MS) characterized by a steady progression of the disease. Many people who suffer from MS experience attacks of their symptoms, but with PPMS, there are no attacks. The disease just steadily gets worse over a long period of time. Some people with PPMS experience periods where the progression may slow down or stop completely, but eventually it will resume. Like most forms of MS, PPMS tends to result in some type of disability.

    Multiple sclerosis (MS) is a disease that affects the nervous system. In a healthy body, nerves are surrounded by a protective layer of fatty tissue called the myelin sheath. If you have MS, that fatty layer is irreversibly damaged by an unknown... More
  2. Multiple Sclerosis Foundation
     
    Primary progressive multiple sclerosis (PPMS) is a type of MS in which the progression of the level of disability continues at a steady rate without any distinct relapses or remissions. Affecting about 10 percent of the MS population, PPMS differs from other forms of the disease in that the initial disease activity is primarily found in the spinal cord, it is usually diagnosed at a later age, and currently there is no approved treatment to control it.
    More Related Answers from Multiple Sclerosis Foundation
    Primary progressive multiple sclerosis (PPMS) is a type of MS in which the progression of the level of disability continues at a steady rate without any distinct relapses or remissions. Affecting about 10 percent of the MS population, PPMS differs... More
  3. Healthwise
     
    Healthwise answered:

    Primary progressive multiple sclerosis (MS) is a form of MS in which the disease is progressive from the start. Symptoms such as muscle weakness, leg dragging, and stiffness become worse, and nerve function deteriorates steadily, though this occurs at different rates in different people.

    Primary progressive MS occurs in just a small number of people with MS. In these people, the illness may be severe from the start with a quick progression of neurological problems over several months. There are no periods when symptoms do not occur (remission).

    There is no cure for MS.

    More Related Answers from Healthwise
    Primary progressive multiple sclerosis (MS) is a form of MS in which the disease is progressive from the start. Symptoms such as muscle weakness, leg dragging, and stiffness become worse, and nerve function deteriorates steadily, though this... More