What medications can interact with ginger?

There is evidence that ginger may increase stomach acid production. As a result, it theoretically may work against the effects of antacids, sucralfate (Carafate®), or anti-reflux medications such as H-2 blockers like ranitidine (Zantac®) or proton pump inhibitors like lansoprazole (Prevacid®). In contrast, other laboratory and animal studies report that ginger may act to protect the stomach.

In theory, ginger may increase the risk of bleeding when taken with blood-thinners (although clear human evidence is lacking). Some examples include aspirin, anticoagulants such as warfarin (Coumadin®) or heparin, anti-platelet drugs such as clopidogrel (Plavix®), and non-steroidal anti-inflammatory drugs such as ibuprofen (Motrin®, Advil®) or naproxen (Naprosyn®, Aleve®).

In theory, large doses of ginger may increase the effects of medications that slow thinking or cause drowsiness, such as benzodiazepines or CNS depressants.

Ginger may also interfere with medications that change the contraction of the heart, including beta-blockers, digoxin, and other heart medications.

Because ginger can theoretically lower blood sugar levels, it may interfere with the effects of insulin or diabetes medications that are taken by mouth.

Ginger may interact with drugs broken down by the liver.

Ginger may also interact with drugs taken for nausea/vomiting, arthritis, blood disorders, cough, high cholesterol, high/low blood pressure, allergies (antihistamines), cancer, inflammation, or weight loss. Use cautiously with antibiotics, antidepressants, antifungals, antiparasitic drugs, antivirals, cyclosporine, erectile dysfunction drugs, stimulants, and estrogens. Caution is advised when taking ginger with drugs that weaken the immune system, due to a possible interaction.

You should read product labels, and discuss all therapies with a qualified healthcare provider. Natural Standard information does not constitute medical advice, diagnosis, or treatment.