What medications can interact with astragalus supplement?

In theory, consumption of the tragacanth (gummy sap) derived from astragalus may reduce the absorption of agents taken by mouth. Therefore, tragacanth and other agents should be taken at separate times.

Astragalus may increase the risk of bleeding when taken with drugs that increase the risk of bleeding. Some examples include aspirin, anticoagulants (blood thinners) such as warfarin (Coumadin®) or heparin, antiplatelet drugs such as clopidogrel (Plavix®), and nonsteroidal anti-inflammatory drugs such as ibuprofen (Motrin®, Advil®) or naproxen (Naprosyn®, Aleve®).

Astragalus may lower blood sugar levels. Caution is advised when using medications that may also lower blood sugar. Patients taking insulin or drugs for diabetes by mouth should be monitored closely by a qualified healthcare professional, including a pharmacist. Medication adjustments may be necessary.

Astragalus may lower blood pressure. At higher doses, it may raise blood pressure. Caution is advised in patients taking drugs, herbs, or supplements that affect blood pressure.

Sedatives may decrease the effects of astragalus. Examples of sedatives include benzodiazepines such as lorazepam (Ativan®) or diazepam (Valium®), barbiturates such as phenobarbital, narcotics such as codeine, some antidepressants, and alcohol.

Astragalus may also interact with anesthetics, antiaging agents, antiarthritic agents, antibiotics, anticancer agents, anti-inflammatory agents, antiobesity agents, antiseizure agents, antiviral agents, beta-blockers, cholesterol-lowering agents, CNS stimulants, colchicine, cyclophosphamide, dimethyl sulfoxide (DMSO), dopamine agonists, drugs for anxiety, drugs that are toxic to the liver, drugs that decrease vascular pressure, drugs that increase urination, drugs that protect against radiation, drugs with hormone activity, gastrointestinal agents, growth hormone, hematological agents, immunosuppressants, inotropes, interferons, nalbuphine, neuromuscular blockers, neuroprotective agents, osteoporosis agents, procarbazine, sedatives, steroids, and vaccines.

You should read product labels, and discuss all therapies with a qualified healthcare provider. Natural Standard information does not constitute medical advice, diagnosis, or treatment.