What should I know before I try a Generally Recognized as Safe (GRAS) item?

GRAS status does not indicate that the substance will not cause an allergic reaction.

If consumers use products containing GRAS substances in greater amounts than intended, it is possible that they may experience a number of undesired effects, including toxicity, as well as interactions with foods, herbs, dietary supplements, and medications.

GRAS status does not assure safety or clinical efficacy of any substance, including those used in herbal products and dietary supplements.

GRAS status is not comprehensive; therefore, it does not indicate that a substance that is safe in one product is safe in all circumstances. For example, a GRAS ingredient that may be safe for the general public may be unsafe in infant formula, where it is consumed in large quantities and as the mainstay of a baby's diet.

Some GRAS substances long considered safe, are currently challenged in light of new or accumulated scientific evidence. For example, in late 2007, The Center for Science in the Public Interest and the American Medical Association questioned the safety of consuming salt (which has GRAS status) in certain quantities. Additional research may be needed to further clarify GRAS status for certain substances.

You should read product labels, and discuss all therapies with a qualified healthcare provider. Natural Standard information does not constitute medical advice, diagnosis, or treatment.