What are complications of pain?

Pain can lead to other conditions, including: fatigue, which may cause impatience and a loss of motivation; sleeplessness, often because pain does not allow the individual to receive a full night's sleep; withdrawal from activity and an increased need to rest; a weakened immune system, leading to frequent infections or illness; depression, which may cause pain to feel worse; other mood changes, such as hopelessness, fear, irritability, anxiety, and stress; loss of mobility, such as such as trouble walking up stairs, standing, or sitting; and disability, which may include not being able to go to work or school or perform other daily activities.

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