What causes Raynaud's phenomenon with scleroderma?
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Johns Hopkins Medicine answered:If you have scleroderma, you may develop Raynaud's phenomenon. Raynaud's phenomenon occurs when your fingertips change color when you are cold. This is caused by a spasm in the small blood vessels in your fingers, and may be caused by having too much collagen in your blood vessel walls, a primary marker of scleroderma.
The spasm also causes the color changes in your fingers. Many people also have Raynaud's attacks in their toes. The color changes of a Raynaud's attack are an exaggeration of what happens normally when you expose your hands to the cold. Everyone will develop cold hands when they are exposed to cold temperatures for a long enough time. However, the normal cold response is a blotchy red and white pattern. The color changes of a Raynaud's attack-white then blue or purple-are very different.
If you have scleroderma, you may develop Raynaud's phenomenon. Raynaud's phenomenon occurs when your fingertips change color when you are cold. This is caused by a spasm in the small blood vessels in your fingers, and may be caused by having too... More

