What are immunomodulators for the treatment of psoriasis?

Topical immunomodulators (TIMs), such as tacrolimus ointment (Protopic) and pimecrolimus cream (Elidel), are eczema drugs sometimes used for psoriasis and may be useful for sensitive, thin-skinned areas, such as the face, or in skin-fold areas (under the breasts, in the groin). But these drugs are still considered investigational for psoriasis, and they can interact with a long list of medications and vaccines, which limits their use.

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