What is duodenal-jejunal bypass surgery for type 2 diabetes?

Duodenal-jejunal bypass (DJB) is an investigational procedure, developed by Dr. Rubino of NewYork-Presbyterian Hospital, which has been used in clinical research studies for patients with type 2 diabetes who are not obese. The procedure can be performed in two technical variants (see Technique below) and has been reported to result in good control of diabetes in the short term. Long-term results are being evaluated through research studies.

The operation consists of a stomach-preserving bypass of a short segment of proximal small intestine, equivalent to the amount of intestine bypassed in a standard Roux-en-Y gastric bypass. DJB may be associated with a sleeve resection of the stomach to reduce potential for marginal ulcerations and increase the weight loss effect if performed in mildly or severely obese patients. Long-term data about the efficacy of this procedure are not yet available.