What are the side effects of Depakote ER?

There are many possible side effects to Depakote ER. The most common of these side effects include: appetite disruption, weight fluctuation, constipation, lack of strength, diarrhea, vomiting, dizziness, sleep disruption, drowsiness, abdominal pain, loss of hair, nausea and indigestion. Possible severe side effects include: extreme allergic reactions; changes in behavior or thought processes; disruption of menstrual cycle; chest pain; disorientation; dark stools or urine; speech problems; disruption of normal urination; fatigue; rapid or irregular heartbeat; hallucinations; loss of hearing; uncontrollable movements of the arms, legs, face, mouth, jaw or tongue; pain in joints; general malaise; loss of appetite, coordination or memory; seizures; moodiness; exaggerated mental conditions; nosebleed; rapid heartbeat; skin conditions, such as redness, swelling or blisters; extreme nausea or vomiting; stomach discomfort; shortness of breath; inflammation of the arms or legs; suicidal thoughts or actions; flu-like symptoms; tremors; bruising; bleeding; disruption of normal vision; and a yellow tint to the eyes or skin. If any of these side effects occurs, immediate medical attention is needed.