What is the risk of long-term estrogen treatment?
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Boston Women's Health Book Collective answered:Long-term estrogen treatment increases a woman's risk of breast cancer. The Nurses Health Study, which followed almost 29,000 women, found a 42 percent increased risk of all types of breast cancer in women who used estrogen alone for 20 or more years. For hormone-sensitive breast cancer, the study found a 48 percent increased risk after 15 years of using estrogen alone. A separate study, the Black Women's Health Study of more than 23,000 black women over the age of 40, found an even larger effect— black woman who take either combination estrogen-progestin products or estrogen alone for 10 years or longer have a 50 percent greater risk of breast cancer.
Long-term estrogen treatment increases a woman's risk of breast cancer. The Nurses Health Study, which followed almost 29,000 women, found a 42 percent increased risk of all types of breast cancer in women who used estrogen alone for 20 or more... More
