How do medications treat male genital problems?

A variety of over-the-counter and prescription medications may be used to treat male genital problems, and they each work in different ways. For genital problems that involve mild pain or swelling, over-the-counter treatments containing aspirin or acetaminophen may help reduce inflammation. Sometimes, medicated antibacterial or anti-inflammatory creams may be applied to the penis or scrotum to kill bacteria and reduce pain. These creams may be available with or without a prescription. Sexually transmitted diseases may need to be treated with prescription medications that kill bacteria or help reduce symptoms. Talk to your doctor if you have questions about medications for your specific genital problem.