What should I know about pantoprazole before taking it?

This question relates to a prescription drug. The answers below are not intended to replace discussions with your doctor. Please contact your healthcare provider for any prescription drug questions.

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  1.  Stacy Wiegman
     
    Stacy Wiegman answered:
    Pantoprazole is a proton pump inhibitor (PPI) taken to decrease the production of acid in the stomach. It may be associated with a risk of broken bones, especially when used long-term or in high doses. Pantoprazole may cause other side effects, such as B-12 deficiency and stomach upset. Make sure you are familiar with the risks and side effects of this drug before beginning to take it, and discuss any concerns with your doctor.

    More Related Answers from Stacy Wiegman
    Pantoprazole is a proton pump inhibitor (PPI) taken to decrease the production of acid in the stomach. It may be associated with a risk of broken bones, especially when used long-term or in high doses. Pantoprazole may cause other side... More
  2. Dr. Sarah LoBisco
     
    Dr. Sarah LoBisco answered:

    Chronic use of PPIs can cause rebound symptoms due to irritation on the stomach lining. Also, microbial infections can occur throughout the GI tract, because stomach acid is used not just for digesting minerals and proteins, but also acts as a natural antimicrobial. (Hence the correlation with C. diff and PPI use). This creates the potential for increased fermentation, from the overgrowth of microbes at the base of the esophageal and stomach juncture.

    This can cause increased rebound acid production and nitrate formation from microbial overgrowth, and nutrient deficiencies in minerals, proteins, and vitamins.

    More Related Answers from Dr. Sarah LoBisco
    Chronic use of PPIs can cause rebound symptoms due to irritation on the stomach lining. Also, microbial infections can occur throughout the GI tract, because stomach acid is used not just for digesting minerals and proteins, but also... More