Kava, an extract of a species of pepper plant (Piper methysticum), is widely touted as a natural alternative to anti-anxiety medications. Although some clinical trials have found that it works, possibly by a mechanism similar to that of benzodiazepines, there are concerns here and abroad about its safety.
After investigating reports that 25 people in Germany and Switzerland developed liver toxicity -- including cirrhosis and liver failure -- following use of products containing kava, the Food and Drug Administration (FDA) advised consumers of the potential risk of severe liver injury.
The FDA has also received several reports of toxic reactions in this country. In one case, a previously healthy young woman required a liver transplant after taking a dietary supplement containing kava. In addition, there was a report several years ago of a patient falling into a coma after using kava with the benzodiazepine alprazolam (Xanax). Following these reports, Germany and Switzerland banned the sale of kava. It's still available in the United States, but in light of the potential danger, you should avoid this herb.
Kava, an extract of a species of pepper plant (Piper methysticum),
is widely touted as a natural alternative to anti-anxiety
medications. Although some clinical trials have found that it
works, possibly by a mechanism similar to that of...
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Dr. Michael Mufson answered:Kava, an extract of a species of pepper plant (Piper methysticum), is widely touted as a natural alternative to anti-anxiety medications. Although some clinical trials have found that it works, possibly by a mechanism similar to that of benzodiazepines, there are concerns here and abroad about its safety.
