Is G6PD deficiency life-threatening?

Only in very rare cases does G6PD deficiency lead to death. Typically, the disorder causes relatively minor symptoms that can be treated at home, ranging from pale yellowish skin to dark-colored urine to fever, rapid heartbeat, and general tiredness. However, in extreme cases, the breakdown of red blood cells that the disorder causes can lead to hospitalization and kidney failure. A blood transfusion or kidney transplant might then be necessary. If not treated, such rare cases could become fatal. However, for the great majority of people with G6PD deficiency, if they are careful to avoid the foods, drugs and other items that might trigger the blood cell breakdown, they should be able to live full, healthy lives with a normal life expectancy.