How does ibuprofen and diphenhydramine treat pain and sleeplessness?
This question relates to a prescription drug. The answers below are not intended to replace discussions with your doctor. Please contact your healthcare provider for any prescription drug questions.
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Stacy Wiegman answered:Commonly sold over-the-counter as Advil PM, the combination drug ibuprofen-diphenhydramine is used to treat minor pain that can cause sleeplessness. Ibuprofen blocks substances in the body that may produce inflammation and cause pain. Diphenhydramine is an antihistamine that acts on the brain to cause drowsiness.
Commonly sold over-the-counter as Advil PM, the combination drug ibuprofen-diphenhydramine is used to treat minor pain that can cause sleeplessness. Ibuprofen blocks substances in the body that may produce inflammation and cause pain.... More

