How does hemolytic-uremic syndrome affect the body?

Hemolytic-uremic syndrome (HUS) affects the body by attacking and damaging red blood cells. When the red blood cells (including the platelets in your blood which help you clot) are damaged, they do not travel properly through your veins. The misshapen cells get stuck in small veins and cause blockages that affect the functioning of your body, most commonly the kidneys. When blood flow to the kidneys is blocked it inhibits your kidneys' ability to remove extra fluid and waste from your body, causing swelling, reduced urine production, and elevated blood pressure.

When your platelets are damaged, your blood's ability to clot, or create a scab, is affected and you bleed very easily. The inability to clot can mimic symptoms of anemia and cause extreme fatigue and blood loss.