Can a mast cell activation disorder make heart disease worse?

Filter 1 answers by contributor:

  • PRACTITIONER
  • GROUP
  • AUTHOR
  • TV PERSONALITY
  • ALL
  1. Brigham and Women's Hospital
     
    Brigham and Women's Hospital answered:
    A spate of recent laboratory studies supports the participation of mast cells in atherosclerosis and in arterial aneurysm formation. Most of these studies derived from observations in mice and using biomarkers of mast cell activation in humans. But direct evidence that mast cells aggravate human cardiovascular disease remains scant. General advice is to heed current guidelines regarding cardiovascular prevention assiduously to minimize any excess risk you might have from an underlying mast cell activation disorder.
    More Related Answers from Brigham and Women's Hospital
    A spate of recent laboratory studies supports the participation of mast cells in atherosclerosis and in arterial aneurysm formation. Most of these studies derived from observations in mice and using biomarkers of mast cell activation in... More