A Answers (1)
Stacy Wiegman, PharmD, Pharmacy, answeredSome people have allergic reactions to vitamin B9 or folic acid. Generally speaking, folic acid is very safe but you should talk to your doctor before using it if you have pernicious anemia, hemolytic anemia, alcoholism, infections or kidney problems. Some medications may also negatively interact with folic acid, including phenytoin, primidone, methotrexate, barbiturates, nitrofurantoin, tetracycline and pyrimethamine. If you are taking any of these medications, talk to your doctor before using folic acid. Side effects may include excitement, irritability, nausea, gas, depression, appetite loss, difficulty sleeping or bad taste in the mouth.