All infants, except those who may be at risk of serious side effects or allergic reaction, should receive the rotavirus vaccine. Children who have already had rotavirus can and still should receive the vaccine to obtain greater immunity against the disease. The rotavirus vaccine is extremely effective, as it prevents up to 87% of all rotavirus cases and 98% of severe cases. It is administered in two or three doses, with each dose spaced apart by a period of weeks. The rotavirus vaccine has not been found to interfere with the effectiveness of any other vaccines, so your child can receive the rotavirus vaccine at the same time that they receive other vaccinations.