Coupled with bladder and pelvic floor retraining, certain medicines have proven helpful in controlling urgency and urge incontinence. A class of medicines called anticholinergics help to decrease the number of voiding and incontinence episodes as well as the volume of any leakage. Oxybutinin and tolterodine are the most commonly used. While these medicines are helpful for bladder control, certain side effects can be bothersome. Dry mouth, dizziness and blurred vision can decrease the tolerability of these agents. Other medicines helpful in controlling the bladder muscles and sphincter are hyoscyamine, amitriptyline, imipramine, and flavoxate.
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Johns Hopkins Medicine answered
Marc Garnick, Oncology, answeredThe most effective drugs for urge incontinence are oxybutynin (Ditropan), tolterodine (Detrol), and some of the tricyclic antidepressants. For incontinence that results from treatments for prostate enlargement -- such as transurethral resection of the prostate (TURP), which may produce bladder instability and urge incontinence -- anticholinergic drugs such as propantheline (Pro-Banthine) and dicyclomine (Bentyl) may help. Other novel therapies are under investigation. All of these medicines may have troublesome side effects and it will be important to discuss with your physician which medicine is likely to be most useful for you.